Imaging-Based Screening Platform Assists Protein Engineering.

2018-12-20 · We demonstrate the power of the screening platform by optimizing a dim far-red-emitting fluorescent protein whose brightness increased several fold using iterative cycles of mutagenesis and platform-based screening. The resulting protein variant mCarmine is useful for imaging cells and structures within live tissue as well as for molecular tagging.

Ubiquigent | Drug Discovery Screening Platform

Ubiquigent''s DUBprofiler™ service is well established as the leading platform for the identification and characterisation of novel DUB inhibitors and has been employed by leading groups in support of their drug discovery programmes. Use the DUBprofiler™ in vitro platform to …

AML Screening & Monitoring | PEP, Sanctions, Adverse …

Achieve a seamlessly AML Compliance process with our integrated all-in-one platform. It covers services from Anti-Money Laundering (AML) screening & monitoring to Counter-Terrorism Financing (CFT) Compliance. Specialised and expertise domain in Sanctions screening, PEPs (Politically Exposed Persons) and Adverse Media Screening.

youPCR™ Plant Screening Platform

youPCR™ Plant Screening Platform for use with a 96-well format thermal cycler Page 2 of 12 Introduction: youPCR™ is a mobile DNA amplification platform that can detect various genetic markers in the cannabis plant. youPCR requires a simple 55-minute hands off lysis of a hole punch from a leaf and a …

Screening Platform

Technology platform for fast and efficient screening of functionalized polymer surfaces. The objective of this project is to develop a novel modular method for screening and characterization of functionalized polymer films and surfaces, and apply it to the technologically highly important field of antifouling surfaces.

Ubiquigent | Drug Discovery Screening Platform

Investment screening platform. Conducting Research on China Made Easy. Our specialists are ready to show you how the Datenna''s platforms can help you understand, analyse and resolve screening cases. Schedule a personalised demo of our investment screening, export control or research funding platform …

In vitro flow cytometry-based screening platform for ...

2016-5-17 · The InVitroFlow screening platform combines cell-free compartmentalization with flow cytometer-based analysis and achieves a throughput of 6.5 × 10 6 events per hour. In a single round of ...

In Vitro Screening

In vitro screening and high-throughput screening are critical aspects of modern drug discovery processes. Prior to the advent of these technologies, screening for biologically active candidate compounds is a major bottleneck in the identification of novel therapeutics. The proper combination of in vitro assays can provide critical information ...

Overview

The Assay Development and Screening Platform (ADSP) has been established in 2010 as a Research Group within the Institute of Molecular Toxicology and Pharmacology.. Research topics:. Ferroptosis Research: Unraveling mechanisms and cellular regulators that induce or block ferroptosis, a regulated non-apoptotic cell-death pathway.; Ubiquitin Signaling: Identification and characterization of ...

Process Screening Platform Options

The Process Screening red triangle menu contains options to customize the display and to save calculated statistics. The options that operate on selected items are also accessible by right-clicking the Column column in the Summary table.

Investment screening platform | Datenna

Investment screening platform. Conducting Research on China Made Easy. Our specialists are ready to show you how the Datenna''s platforms can help you understand, analyse and resolve screening cases. Schedule a personalised demo of our investment screening, export control or research funding platform …

Axcelead_en | HTS(High-throughput screening)

2021-6-8 · Assay development and high-throughput screening platformscovering a wide range of target classes. Platforms are available for all major target classes and phenotypes. Axcelead proposes and conducts suitable material preparation (recombinant proteins and stable cell lines) for your HTS. Major AXL assay platforms.

i3 Platform

I3 Platform. Customers and Partners benefit from access to the industry''s most advanced web-based platform for ordering occupational screening services online and integration with all major laboratories and occupational clinics. Combined, these services and integrations connect our Customers and Partners to a simple, convenient screening process.

Hit identification

Hit identification. Evotec has a strong expertise in hit identification and can support its clients screening campaigns through multiple platforms including virtual, biochemical, biophysical, cell and phenotypic based screening with high-throughput capabilities. For screening campaigns, Evotec has the flexibility to screen large client compound ...

Screening Platforms and Automation

2020-12-18 · All screens are automated in dispensing drugs and compounds via tips, pintools and acoustic methods. Our screening platform is built upon several key automations: Labcyte Echo 550: acoustic dispenser integrated into an Access workstation with a Cytomat cell …

Federal Polytechnic Nekede | Start Admissions Screening

2021-8-28 · Admissions Screening Platform . Enter Application No & O''level Verification Payment RRR to Login! Application No: RRR: Verify; FPNO Portal | Whatsapp Chat: ONLINE | Call 24/7 09090368743, Email: [email protected] . Return Home ...

A Versatile High Throughput Screening Platform for Plant ...

A Versatile High Throughput Screening Platform for Plant Metabolic Engineering Highlights the Major Role of ABI3 in Lipid Metabolism Regulation Front Plant Sci. 2020 Mar 17;11:288. doi: 10.3389/fpls.2020.00288. eCollection 2020. Authors Benjamin Pouvreau 1 ...

Screening Platforms | SGC

2021-8-29 · Also known as Thermal Shift Assay. The assay principle is based on the stabilization of the native protein structure upon the ligand binding. The rank order of ligand binding and the estimate of the binding energy can be obtained by comparing the Tm …

A T-flask based screening platform for evaluating and ...

2007-8-18 · This paper presents a T-flask based screening platform for evaluating and identifying plant hydrolysates for cell culture processes. The development of this platform was driven by an urgent need of replacing a soy hydrolysate that was no longer available for the fed-batch process of recombinant Sp2/0 cell culture expressing a humanized antibody. Series of small-scale experiments in T-flasks ...

Magic™ Detergent Screening Platform

Magic™ Detergent Screening Platform. Creative Biolabs provides the powerful detergent screening platform to find the suitable detergents (detergents and short-chain lipids) or detergent mixtures for our customers'' membrane proteins. One of the most common difficulties in handling membrane proteins is the choice of detergents (detergents or ...

Drug Screening Platforms – Initiative for Neural Science ...

Initiative for Neural Science, Disease & Engineering. High-throughput screening approaches are utilized by pharmaceutical companies to rapidly evaluate new and/or existing chemical entities for desired effects on cells or cellular processes. Through the use of automated …

Magic™ Lipid Screening Platform

Magic™ Lipid Screening Platform. Creative Biolabs provides the powerful lipid screening platform to facilitate the research, development, and application of membrane proteins. We have around 50 lipids available for screening on this platform, both natural and artificial lipids. Lipids alone …

Screening Platform | Global Health Innovative Technology Fund

GHIT Fund RFP Screening Platform 2021-002. The GHIT Fund established a Drug Discovery Screening Platform in early 2013 to facilitate the screening of compound libraries for identification of novel compounds for malaria, tuberculosis, Chagas disease and leishmaniasis.

Compound Screening Platform, BOC Sciences

Compound Screening Platform Price Inquiry Compound screening in new drug research is the process of selecting compounds with higher activity for a specific target from a large number of compounds or new compounds through standardized experimental methods, and its essence is the process of experimenting with compounds for pharmacological activity.

Optimization of a High-Throughput 384-Well Plate-Based ...

2020-4-25 · Here, we miniaturized a 96-well plate (96WP) screening platform, into a 384-well plate (384WP) format, based on a sequential viability and biomass measurements for the assessment of anti-biofilm activity. During the assay optimization process, different parameters were evaluated while using Staphylococcus aureus and Pseudomonas aeruginosa as ...

An ultrahigh‐throughput screening platform based on flow ...

2020-9-28 · An ultrahigh‐throughput screening platform based on flow cytometric droplet sorting for mining novel enzymes from metagenomic libraries Environmental Microbiology ( IF 5.491) Pub Date : 2020-09-28, DOI: 10.1111/1462-2920.15257

A Photoaffinity‐Based Fragment‐Screening Platform for ...

2020-8-3 · Fragment screening offers an efficient approach to explore chemical space. Presented here is a fragment-screening platform, termed PhABits (PhotoAffinity Bits), which utilizes a library of photoreactive fragments to covalently capture fragment–protein interactions.

High-throughput screening platform for solid electrolytes ...

2020-5-21 · The combination of a materials database with high-throughput ion-transport calculations is an effective approach to screen for promising solid electrolytes. However, automating the complicated ...

(PDF) In vitro flow cytometry-based screening platform for ...

2016-5-17 · InVitroFlow was validated by screening of a random cellulase mutant library employing a novel. screening system (based on the substrate uorescein-di- β -D-cellobioside), and yielded signi cantly ...

Drug screening platform

2018-10-25 · As high content screening system and automated high throughput drug screening robotic workstation was established during the period 2006~2010, the platform has reached the world advanced level and leading position in China. There are 18 full time staff members in the platform to perform screening work for drugs of major diseases.

Screening Platform – Centro Investigación Príncipe Felipe

2021-8-20 · Screening Platform. The CIPF Screening Platform Service was created to support the evaluation of biological and pharmacological compound libraries—whether in-house at the CIPF or from external entities. This service has created two chemical compound libraries ( Myriad and Prestwick ), which combined, contain more than 11,000 compounds.

Sanctions Screening – Hyperflow Platform

Through the HM Treasury (the government''s economic and finance ministry), the Chancellor of the Exchequer informs that, in accordance with The Money Laundering, Terrorist Financing and Transfer of Funds (Information on the Payer) Regulations 2017, obligated institutions apply …

Evaluation of comprehensive chromosome screening platforms ...

Purpose: A subset of preimplantation embryos identified as euploid may in fact possess both whole and sub-chromosomal mosaicism, raising concerns regarding the predictive value of current comprehensive chromosome screening (CCS) methods utilizing a single biopsy. Current CCS methods may be capable of detecting sub-chromosomal mosaicism in a trophectoderm biopsy by examining intermediate levels ...

Droplet-based microfluidic platform for high-throughput ...

2021-5-31 · Our platform enabled the entire screening process for the library detection and sorting to be performed within 1 day, and the throughput could reach 10,000 variants per hour, which is a hundred ...

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